T-LAB PRP Tube
Each kit contains two T−LAB PRP Tubes. Each tube has a volume of 10 ml prefilled with 1 ml of anticoagulant. The vacuum in the tubes facilitate blood collection. The Tubes are sterile both inside and outside. Our tubes definitely don't contain ficolls or gels. It has no hemolytic effect, it is biocompatible and PRP obtained with these tubes can be legally injected back into humans.
There is 1 piece of re-suspension tube in each kit. It is a sterile empty tube with a volume of 10 ml. The purpose of this tube is to homogenize the PRP collected from both PRP tubes by combining them.
The kit contains two sterile syringes of a 5ml and 1ml volume. While the 5 ml syringe is used to collect PRP and transfer it to the re−suspension tube, the 1 ml syringe is used for PRP injection.
The kit contains 3 needles, one 18Gx90mm long needle, one 21Gx40mm and one 30Gx13mm. The long needle is used for collecting and transferring the PRP to the re−suspension tube while the 21G needle is used to withdraw PRP from the re−suspension tube. The 30G needle is used for intradermal administration.
Blood Collection Set
The kit contains a two-piece phlebotomy set. Thanks to this set, you do not need an additional apparatus to collect blood into the tubes and you can quickly perform blood collection.
9 Reasons to Prefer T-LAB
T-LAB Pure PRP protocol has demonstrated that it achieves a platelet recovery rate between 80-95% in cell counts conducted by neutral institutions. Thus, it guarantees that an optimal end product will be acquired from the blood taken from the patient. Platelet recovery rate is described in the DEPA Classification publication, which is an objective and scientific method that shows how much of the whole platelet count in the whole blood taken from the patient, regardless of concentration, are recovered as a percentage.
T-LAB has proven to provide purity between 95-99% in analyzes conducted by neutral institutions with the pure PRP protocol. Purity in PRP is a calculation that shows the Platelet to RBC and WBC ratio and therefore provides an accurate depletion rate of unwanted WBC and RBC cells. The less presence of cells other than platelets in PRP reduces risks such as burning and redness during PRP application. The purity rate is explained in the DEPA Classification publication, which is an objective and scientific method.
The classic PRP definition is referred to as Amber or LR-PRP, it aims to collect the buffycoat layer. Since this method focuses on yielding a high PRP concentrate, it is successfully applied in areas such as wrinkle treatment. However, today, the use of the pure PRP method, which does not result in buffycoat formation and makes use of all the plasma, is becoming more prevalent. Although the pure PRP method yields a lower concentration, it offers higher platelet recovery rate and a purer PRP content, thus providing the patient with a higher dose of platelet injection. Both methods can be obtained by using different protocols with T−LAB PRP Kit. The physician can select the desired protocol according to the purpose of the application.
T-LAB PRP Tubes have no similarities with laboratory tubes in terms of production and legal conditions, except that they are figuratively similar to laboratory (IVD) tubes. T−LAB PRP tubes are products that are certified with a CE and secured with Class IIb hence PRP obtained with T-LAB PRP Tubes have achieved the status of an end biological product that can be safely reinjected back to the patient according to the medical device directives. Laboratory tubes, on the other hand, are products that are subject to the IVD directive, thus patient injection of PRP achieved with these tubes is not legal and carries risks, IVD tubes are produced only for the purpose of examining the patient's blood in the laboratory environment.
Unlike anticoagulant-free products sold for obtaining PRP, the T−LAB PRP Kit offers you anticoagulant in the right amount to ensure the best results. It eliminates problems such as the risk of not mixing the anticoagulant at the right ratio, contamination, and the procurement process. The anticoagulant contained in the T−LAB PRP Tubes has been passed through aseptic filters, sterilized and specially manufactured for injection back to the patient. It contains 3.2% sodium citrate, does not contain dextrose or different components such as ACD-A and is not a drug.
When the blood is spun in order to obtain PRP, its components are subject to a force , this force leads to the formation of Cell clusters where platelets aggregate especially with the Amber PRP protocol, the resuspension tube offers a sterile environment to release these clusters. The end product is gently shaken for 30-60 seconds to ensure that the PRP transferred into the re-suspension tube achieves a more homogeneous structure , thus allowing each injection to provide a more homogeneous platelet distribution, especially in skin applications.
T-LAB PRP Kit has been used in more than ten scientific publications in different fields and has proven its effectiveness, additionally more scientific publications are ongoing. For more information about publications, please visit the T−LAB PRP Kit / Publications page.
T-Lab is the first gel-free PRP Tube manufacturer. Although gel products are introduced as allergy-free, these gels are usually petrochemical products. T−Lab has decided to develop products and protocols that do not use gel following findings of gel structures disintegration under high centrifugal speeds being mixed into the PRP. In addition to these risks, the gel structure can also reduce the concentration by trapping some of the platelets. The only practical benefit of the gel is that the tube can be turned upside down thus allowing an easier plasma collection, However the PRP layer can be easily collected and the risks of the gel can be eliminated with the long needle in the T−LAB PRP Kit without the need for this procedure.
A CE certificate does not necessarily indicate that a product can be injected into humans. The applicable directive (MDD or MDR directive) for PRP Kits are class IIA, IIb or III CE certificates. These classes are a testament to the fact that blood obtained with kits falling under those categories is hemolytically tested and approved for human injection. Laboratory tubes are also CE certified, but these products are produced in accordance with IVD or IVDR directives, not MDD or MDR. When the product catalogs are examined, the phrase "Do not inject to human" can be seen easily. Injecting PRP obtained with such tubes is not clinically permitted and complications that may result from otherwise applications are entirely the responsibility of the physician. Because it has been made clear in the product catalog that this should not be done. For this reason, using a product with the proper medical device CE certificate is a status that protects the physician.
What is PRP?
It is a form of treatment in which platelets (a.k.a. thrombocytes), which are the main components of blood, are separated from other blood cells, erythrocytes and leukocytes, and then this group of cell is injected back into the patient as an autologous therapy. The full blood taken is treated with anticoagulants to prevent out-of-body clotting, then fractionated into layers of blood components by a centrifugal procedure. The platelet-rich buffy coat layer is taken from the separated layers and injected back into the patient. The average number of platelets which ranges between 150-400 thousand in microliters in a normal person is increased by 2 to 4 times with this process. Colorless and nucleus-free platelet cells in granular structure that play a role in the blood clotting mechanism play a key role in tissue regeneration with growth factors such as PDGF, IGF, EGF, TGF-β1-2, VEGF, PDF, PDEGF, PDAF they secrete.
How Does PRP Work? Where is it used?
Skin damage repairAssist in hair transplantationOrthopedic treatmentsRepairs to muscle and connective tissueEye treatmentsDental treatmentsVeterinary use
PRP is used as an autologous treatment in different branches to repair a damaged tissue. Skin, hair treatments, joint and connective tissue problems are the main ones. The effectiveness of PRP increases with contact with damaged tissue which prompts growth factors secretion in the target area. For this reason, in addition to being effective as a standalone treatment, it can show higher effectiveness in combination with controlled damage methods such as microneedling, fractional laser in applications such as skin rejuvenation, crack appearance and acne removal, and allows the skin to regenerate itself by producing collagen. At the end of a few sessions, it gives permanent and fast results in many skin problems, from wrinkle marks to acne spots.
In hair treatments, VEGF growth factors help to increase vascularization and support the nutrition of hair follicles. In this way, it can be used as an efficient adjuvant before and after hair transplantation as well as in hair loss.
The same treatment mechanism is effective in ensuring cartilage healing in joint problems and repairing muscle and connective tissues. In addition, its use in the treatment of numerous disorders such as intraovarian insufficiency in fertility-assisted treatments, dry eye in eye treatments, corneal ulcer, erectile dysfunction disorder in urology, wound treatments in general surgery, diabetic foot wounds has been supported by scientific publications. It can also be used in veterinary medicine in all areas of use on humans.
Does PRP Have Side Effects?
Since PRP is an autologous application obtained from one's own blood and reinjected into the same individual, it has no major side effects. However, it is not recommended to use it in patients with autoimmune disease, cancer history, pregnancy or suspected pregnancy because there are not enough scientific studies. However, its effectiveness is low in patients with thrombocytopenia who use blood thinners (anticoagulant) drugs.
However, as with all medical applications, contamination that may occur during the removal, treatment and re-injection of blood outside the body carries the risks of infection. The use of approved PRP kits is vitally important for this. In order to avoid these risks, key factors such as the use of the correct kit, i.e. T−LAB PRP Kit, which are completely sterile and free of any drugs, supplied with carefully manufactured anticoagulant in them should be preferred. In particular, the use of laboratory tubes (IVD) should be only limited to biocompatibility test, hemolytic effect test, scientific publications produced for testing of blood outside the body as the anticoagulant it contains is not cleared for human injection therefore is not allowed for clinical use. T−LAB PRP Tube and T−LAB Re-Suspension Tube have been tested against all these effects and are certified as suitable for clinical use with a CE Class IIb certificate.